Article

An inductive, supervised approach for predicting gene–disease associations using phenotype ontologies

2025-05-13

Abstract excerpt

<h4>Motivation</h4> Predicting gene–disease associations (GDAs) is the problem to determine which gene is associated with a disease. The problem can be framed as a ranking problem where genes are ranked based on a set of phenotypes using a measure of phenotype similarity. When phenotypes are described using phenotype ontologies, ontology-based semantic similarity measures are used. Traditional semantic similarity...

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Literature Corpus work: ff571757-aee8-5f7b-bb64-329f4cdafaee
DOI: 10.1101/2025.05.07.652682

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