Article

Adaptation and inhibition control pathological synchronization in a model of focal epileptic seizure

2018-05-02

Abstract excerpt

Pharmacoresistant epilepsy is a common neurological disorder in which increased neuronal intrinsic excitability and synaptic excitation lead to pathologically synchronous behavior in the brain. In the majority of experimental and theoretical epilepsy models, epilepsy is associated with reduced inhibition in the pathological neural circuits, yet effects of intrinsic excitability are usually not explicitly analyzed....

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Literature Corpus work: feeed5ec-2389-53c5-9e8b-d5afff773430
DOI: 10.1101/312561

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