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Systematic analysis identifies CDKN2A as a prognostic biomarker for hepatocellular carcinoma

2025-07-23

Abstract excerpt

<title>Abstract</title> <p>Background Hepatocellular carcinoma (HCC) ranks as the fifth most prevalent malignancy worldwide. Disruptions in copper homeostasis adversely affect liver function. Cuproptosis, a recently defined form of regulated cell death triggered by intracellular copper accumulation, disrupts the tricarboxylic acid cycle and mitochondrial respiration. However, the specific roles and mechanisms of...

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Literature Corpus work
fe97f78d-a9b6-55d1-ba9d-fb38aeb90f46
DOI
10.21203/rs.3.rs-7074933/v1
Open publication

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Systematic analysis identifies CDKN2A as a prognostic biomarker for hepatocellular carcinomaDOI 10.21203/rs.3.rs-7074933/v1
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