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Article

A prognostic signature of cuproptosis and TCA-related genes for hepatocellular carcinoma

17 Oct 2022

Abstract excerpt

Background Hepatocellular carcinoma (HCC) is the most common malignant tumor of the liver. Cuproptosis is a newly defined form of cell death. Copper ion induces cell death by binding to the tricarboxylic acid cycle (TCA). The effect of cuproptosis-related and TCA-related genes on the clinical prognosis of HCC is still unclear. In this study, we explores the genetic changes of cuproptosis-related genes that affect...

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PMID: 36324575
DOI: 10.3389/fonc.2022.1040736

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