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Dietary Fiber, Gut Microbiota, and Chronic Inflammation in Colorectal Cancer Prevention

2026-06-23

Abstract excerpt

Colorectal cancer (CRC) ranks as the third most common cancer and second leading cause of cancer-related mortality worldwide with significant geographic disparities and rising burden in regions like Nepal. Chronic inflammation like inflammatory bowel disease (IBD) drives colorectal carcinogenesis through key pathways including NF-κB, COX-2/PGE2, IL-6/STAT3, and IL-23/Th17. They create a pro-tumorigenic microenviro...

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Literature Corpus work
fe955390-35d5-5ebf-bb7a-3a4c56697749
DOI
10.20944/preprints202606.1614.v1
Open publication

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