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Integrated network pharmacology and transcriptomics identify PPP1CA and LCK as biomarkers of Tougu Xuejie San in rheumatoid arthritis

2026-05-25

Abstract excerpt

<title>Abstract</title> <p>Rheumatoid arthritis (RA) is a chronic autoimmune disorder with limited therapeutic options. Tougu Xuejie San (TGXJS), a traditional Chinese medicine formula, exhibits anti-inflammatory and immunomodulatory activities in RA, yet its molecular mechanisms remain unclear. We integrated network pharmacology, transcriptome analysis, machine learning, and experimental validation to identify k...

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Literature Corpus work
fdff5319-8ba9-514c-8e60-02ef27858a25
DOI
10.21203/rs.3.rs-9075320/v1
Open publication

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Integrated network pharmacology and transcriptomics identify PPP1CA and LCK as biomarkers of Tougu Xuejie San in rheumatoid arthritisDOI 10.21203/rs.3.rs-9075320/v1
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