Article

Spontaneous Pregnancy and Biochemical Improvement in a Woman with Non-Classical Congenital Adrenal Hyperplasia Treated with Modified-Release Hydrocortisone

2025-08-26

Abstract excerpt

<h4>Introduction: </h4> Non-classical congenital adrenal hyperplasia (NCCAH) due to 21-hydroxylase deficiency is associated with chronic hyperandrogenism, menstrual irregularities, and subfertility. Modifiedrelease hydrocortisone (MRHC) therapy, which mimics physiological cortisol rhythms, may enhance reproductive outcomes. Clinical experience with MRHC in the preconception setting is still limited. Case presentat...

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Literature Corpus work: fd732c9e-5242-5ebd-a4e0-0afe02f65ac7
DOI: 10.22541/au.175624407.72730245/v1

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