Article

Targeting Metainflammation in Hidradenitis Suppurativa: The Emerging Role of GLP-1 Receptor Agonists and Metabolic Pharmacotherapies

2026-08-19

Abstract excerpt

Hidradenitis suppurativa (HS) is a systemic inflammatory skin disease associated with obesity, insulin resistance, and visceral adiposity. Chronic metainflammation may contribute to cutaneous disease activity, while metabolic dysregulation potentially occurs independently of body mass index (BMI). Additionally, emerging metabolic pharmacotherapies may provide weight-dependent and weight-independent immunomodulator...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: fd2243b2-fa66-5f4c-8737-1f6bad65c743
DOI: 10.20944/preprints202608.1275.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Targeting Metainflammation in Hidradenitis Suppurativa: The Emerging Role of GLP-1 Receptor Agonists and Metabolic PharmacotherapiesDOI 10.20944/preprints202608.1275.v1Read

Hidradenitis SuppurativaSemantic proximity Read

Hidradenitis suppurativa: an update on epidemiology, phenotypes, diagnosis, pathogenesis, comorbidities and quality of life.Semantic proximity Read

A systematic review and critical evaluation of inflammatory cytokine associations in hidradenitis suppurativaSemantic proximity Read

Metabolic Repression of Autophagy Drives Inflammation, Pain, and Malodor in Hidradenitis SuppurativaSemantic proximity Read

Leveraging genotypes and phenotypes to implement precision medicine in hidradenitis suppurativa management.Semantic proximity Read

Hidradenitis suppurativa, a review of pathogenesis, associations and management. Part 1.Semantic proximity Read

Transcriptome Meta-Analysis Confirms the Hidradenitis Suppurativa Pathogenic Triad: Upregulated Inflammation, Altered Epithelial Organization, and Dysregulated Metabolic SignalingSemantic proximity Read

Impaired Molecular Mechanisms Contributing to Chronic Pain in Patients with Hidradenitis Suppurativa: Exploring Potential Biomarkers and Therapeutic TargetsSemantic proximity Read

Decreased HDL-C in Hidradenitis Suppurativa: Association with Systemic Inflammatory Phenotype and Implications for Risk StratificationSemantic proximity Read

Unravelling the complex pathogenesis of hidradenitis suppurativa.Semantic proximity Read

The impact of innate immunity and epigenetics in the pathogenesis of hidradenitis suppurativaSemantic proximity Read

Belgian Patients of the European Registry for Hidradenitis Suppurativa (ERHS-Be): Data, Scores, and Phenotypes since 2015.Semantic proximity Read