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Metabolic Repression of Autophagy Drives Inflammation, Pain, and Malodor in Hidradenitis Suppurativa

2026-01-29

Abstract excerpt

<h4>ABSTRACT</h4> Hidradenitis suppurativa (HS) is a debilitating and underdiagnosed inflammatory skin disease with limited therapeutic options due to an incomplete understanding of its molecular and immunopathogenic basis. Using an integrated multi-omics approach, we delineate convergent pathways linking dysregulated autophagy, malodour, and pain in HS. Lesional tissues exhibited sustained autophagy repression,...

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Literature Corpus work
83c0559c-ec6b-5d3f-9d72-c10d5d1a25e6
DOI
10.64898/2026.01.26.700194
Open publication

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