Article

Elucidating photoreceptor gene function with in-vivo CRISPR knock-out perturbation assay

2025-10-27

Abstract excerpt

<title>Abstract</title> <p> Over the past two decades, considerable progress has been made in cataloguing genes and active chromatin elements in humans. However, despite these efforts, less than a quarter of genes have been assigned a function in the context of human disease, which limits our ability to interpret clinical genome sequencing results. In the field of inherited retinal diseases, 30–40% of cases rema...

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Literature Corpus work: fd06b4a8-a23e-5742-8ff1-6860ffbd5e72
DOI: 10.21203/rs.3.rs-7670521/v1

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