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Article

CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa: A Brief Methodology.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Wu Wen-Hsuan, Tsai Yi-Ting, Justus Sally, Cho Galaxy Y, Sengillo Jesse D, Xu Yu, Cabral Thiago, Lin Chyuan-Sheng, Bassuk Alexander G, Mahajan Vinit B, Tsang Stephen H

Abstract excerpt

CRISPR/Cas9 genome engineering is currently the leading genome surgery technology in most genetics laboratories. Combined with other complementary techniques, it serves as a powerful tool for uncovering genotype-phenotype correlations. Here, we describe a simplified protocol that was used in our publication, CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa, providing an...

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Identifiers

PMID: 29188514
DOI: 10.1007/978-1-4939-7522-8_13
PMCID: PMC9119419

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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