Large-scale whole-genome sequencing of three diverse Asian populations in Singapore

Abstract excerpt

Asian populations are currently underrepresented in human genetics research. Here we present whole-genome sequencing data of 4,810 Singaporeans from three diverse ethnic groups: 2,780 Chinese, 903 Malays, and 1,127 Indians. Despite a medium depth of 13.7×, we achieved essentially perfect (>99.8%) sensitivity and accuracy for detecting common variants and good sensitivity (>89%) for detecting extremely rare variant...

Topics

Open a Topic to create a Post that cites this publication.

• Asian People
• Genetics, Population
• Genome, Human
• Genome-Wide Association Study
• Genomic Structural Variation
• Linkage Disequilibrium
• Singapore
• Whole Genome Sequencing

Identifiers and source

Literature Corpus work

fc903c95-64de-557e-8dbc-558db2cd9e9c

DOI

10.1101/390070