Article

Predicting Drug Response with Multi-Task Gradient-Boosted Trees in Epilepsy

2025-08-13

Abstract excerpt

<h4>Motivation</h4> Despite the availability of numerous anti-seizure medications (ASMs), drug resistance remains a major issue for people with epilepsy. The probability of achieving seizure freedom diminishes with each unsuccessful drug trial, and the impact of genetic and clinical markers on ASM response remains unclear. To address this issue, we used state-of-the-art machine learning (ML) methods to predict th...

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Literature Corpus work: fbf885ba-aa62-59ff-8643-73a0455162fe
DOI: 10.1101/2025.08.12.669672

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