Article

Patient Informed Domain Adaptation Improves Clinical Drug Response Prediction

2021-08-09

Abstract excerpt

<h4>ABSTRACT</h4> In-silico modeling of patient clinical drug response (CDR) promises to revolutionize personalized cancer treatment. State-of-the-art CDR predictions are usually based on cancer cell line drug perturbation profiles. However, prediction performance is limited due to the inherent differences between cancer cell lines and primary tumors. In addition, current computational models generally do not lev...

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Literature Corpus work: fbaf9e24-d78f-5496-a8a3-2fdfe98847a1
DOI: 10.1101/2021.08.07.455527

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