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Article

Ocular disease mechanisms elucidated by genetics of human fetal retinal pigment epithelium gene expression

2018-10-18

Abstract excerpt

The eye is an intricate organ with limited representation in large-scale functional genomics datasets. The retinal pigment epithelium (RPE) serves vital roles in ocular development and retinal homeostasis. We interrogated the genetics of gene expression of cultured human fetal RPE (fRPE) cells under two metabolic conditions. Genes with disproportionately high fRPE expression are enriched for genes related to inher...

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Literature Corpus work
fb34c8ad-4154-5460-a933-42b2275087a0
DOI
10.1101/446799
Open publication

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Ocular disease mechanisms elucidated by genetics of human fetal retinal pigment epithelium gene expressionDOI 10.1101/446799
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