Article

Genetic analysis of the novel SARS-CoV-2 host receptor <i>TMPRSS2</i> in different populations

2020-04-24

Abstract excerpt

The infection coronavirus disease 2019 (COVID-19) is caused by a virus classified as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). At cellular level, virus infection initiates with binding of viral particles to the host surface cellular receptor angiotensin converting enzyme 2 (ACE2). SARS-CoV-2 engages ACE2 as the entry receptor and employs the cellular serine protease 2 (TMPRSS2) for S protein pr...

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Literature Corpus work: fab2329c-c901-5da5-b5ce-d8ad2aebf57f
DOI: 10.1101/2020.04.23.057190

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