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Molecular Classification and Interpretation of Amyotrophic Lateral Sclerosis Using Deep Convolution Neural Networks and Shapley Values

2021-10-04

Abstract excerpt

Amyotrophic Lateral Sclerosis (ALS) is a prototypical neurodegenerative disease characterized by progressive degeneration of motor neurons to severely effect the functionality to control voluntary muscle movement. Most of the non additive genetic aberrations responsible for ALS make its molecular classification very challenging along with limited sample size, curse of dimensionality, class imbalance and noise in t...

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Literature Corpus work
fa9f67b2-8bc2-54a0-b003-2061203a635a
DOI
10.20944/preprints202110.0059.v1
Open publication

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