Back to search

Article

Social history and exposure to pathogen signals modulate social status effects on gene regulation in rhesus macaques

2019-02-18

Abstract excerpt

Social experiences are an important predictor of disease susceptibility and survival in humans and other social mammals. Chronic social stress is thought to generate a pro-inflammatory state characterized by elevated antibacterial defenses and reduced investment in antiviral defense. Here, we manipulated long-term social status in female rhesus macaques to show that social subordination alters the gene expression...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
fa5d3675-390f-52e3-9dbc-fb9b9a0bf184
DOI
10.1101/552356
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Social history and exposure to pathogen signals modulate social status effects on gene regulation in rhesus macaquesDOI 10.1101/552356
Dominance rank-associated immune gene expression is widespread, sex-specific, and a precursor to high social status in wild male baboonsSemantic proximity
Social status alters chromatin accessibility and the gene regulatory response to glucocorticoid stimulation in rhesus macaquesSemantic proximity
Adaptive immune responses to vaccination reflect social status at first exposure in female rhesus macaquesSemantic proximity
Human Social GenomicsSemantic proximity
A female-biased gene expression signature of dominance in cooperatively breeding meerkatsSemantic proximity
The biology of aging in a social world: insights from free-ranging rhesus macaquesSemantic proximity
Social Stress Alters Immune Response and Results in Higher Viral Load During Acute SIV Infection in a Pigtailed Macaque Model of HIVSemantic proximity
Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeysSemantic proximity
A depauperate immune repertoire precedes evolution of sociality in bees.Semantic proximity
Affiliative behavioural phenotype and microglial activation predict social decision-making following immune activation.Semantic proximity
Human sickness behavior: Ultimate and proximate explanations.Semantic proximity
Risk and resilience: early manipulation of macaque social experience and persistent behavioral and neurophysiological outcomes.Semantic proximity
Select a neighboring publication to make it the new centre.