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Article

The glycolytic PKM gene is associated with immune infiltrates and therapeutic response of pancreatic cancer

2025-12-16

Abstract excerpt

<title>Abstract</title> <p>Background Cancer cells undergo metabolic reprogramming to sustain proliferation and metastasis, with the glycolytic pathway playing a key role. This study investigates the prognostic significance, immune infiltration, and treatment response of the glycolysis-related gene Pyruvate Kinase M (PKM) in pancreatic cancer. Methods Pancreatic cancer samples were obtained from GEO and TCGA data...

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Literature Corpus work
fa4a44e4-3852-5543-b6a4-466ac494df12
DOI
10.21203/rs.3.rs-7676660/v1
Open publication

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