Article

Multiplex logic processing isothermal diagnostic assays for an evolving virus

2018-09-23

Abstract excerpt

We have developed a generalizable ‘smart molecular diagnostic’ capable of accurate point-of-care (POC) detection of variable nucleic acid targets. Our one-pot isothermal assay relies on multiplex execution of four loop-mediated isothermal amplification reactions, with primers that are degenerate and redundant, thereby increasing the breadth of targets while reducing the probability of amplification failure. An eas...

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Identifiers and source

Literature Corpus work: fa20884e-9432-50f9-b982-44f2bafa7cfd
DOI: 10.1101/424440

Open publication

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