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Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 and a variant of concern in ferrets

2021-07-30

Abstract excerpt

<title>Abstract</title> <p>Remdesivir is the only small-molecule antiviral approved to date for COVID-19 treatment, but its wider use is limited by intravenous delivery. An orally bioavailable remdesivir analog may boost therapeutic benefit by facilitating early administration to non-hospitalized patients. This study characterized the anti-SARS-CoV-2 efficacy of GS-621763, an oral prodrug of remdesivir parent nuc...

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Literature Corpus work
f953ec93-3606-5dd8-ac73-bceb47cc60c3
DOI
10.21203/rs.3.rs-662905/v1
Open publication

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Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 and a variant of concern in ferretsDOI 10.21203/rs.3.rs-662905/v1
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