Article

In-vivo whole-cortex estimation of excitation-inhibition ratio indexes cortical maturation and cognitive ability in youth

2023-06-22

Abstract excerpt

A balanced excitation-inhibition ratio (E/I ratio) is critical for healthy brain function, but challenging to measure in-vivo in humans. Here we present an approach to non-invasively estimate whole-cortex E/I ratio by fitting a large-scale biophysically plausible model to resting-state functional MRI (fMRI) data. We first confirm our model generates realistic brain dynamics in the Human Connectome Project. Next, w...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f93c172b-05a8-52ef-8ab9-712c03f08c25
DOI: 10.1101/2023.06.22.546023

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

In-vivo whole-cortex estimation of excitation-inhibition ratio indexes cortical maturation and cognitive ability in youthDOI 10.1101/2023.06.22.546023Read

Regional patterns of human cortex development correlate with underlying neurobiologySemantic proximity Read

Spatial and temporal pattern of structure-function coupling of human brain connectome with developmentSemantic proximity Read

Brain anatomy and molecular signaling predict neurophysiological dynamics across the lifespanSemantic proximity Read

Autism Spectrum Disorder is characterized by reduced spatial autocorrelation of the excitation/inhibition ratioSemantic proximity Read

Developmental coupling of cerebral blood flow and fMRI fluctuations in youthSemantic proximity Read

Trajectories of Response Inhibition Development in AdolescenceSemantic proximity Read

Excitation/Inhibition balance relates to cognitive function and gene expression in Temporal Lobe Epilepsy: an hdEEG assessment with aperiodic exponentSemantic proximity Read

Combining Aperiodic 1/f Slopes and Brain Simulation: An EEG/MEG Proxy Marker of Excitation/Inhibition Imbalance in Alzheimer’s DiseaseSemantic proximity Read

Brain Functional-Structural Gradient Coupling Reflects Development, Behavior and Genetic InfluencesSemantic proximity Read

Optimization of Energy State Transition Trajectory Supports the Development of Executive Function During YouthSemantic proximity Read

Intrinsic structural covariation links cerebellum subregions to the cerebral cortexSemantic proximity Read

A Bias-Accounting Meta-Analytic Approach Refines and Expands the Cerebellar Behavioral TopographySemantic proximity Read