Back to search

Article

AVDB: The Arab Variation and Disease Burden Database

2025-08-27

Abstract excerpt

<h4>Motivation</h4> Public genomic databases are crucial to precision medicine but often lack representation from Arab populations, which have distinct genetic structures due to high consanguinity rates. <h4>Results</h4> We present the Arab Variation and Disease Burden Database (AVDB), derived from 1,194 exomes of Emirati individuals, comprising 2,481 curated variants across 850 genes. AVDB provides pathogenicit...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
f89dde4f-1d93-5d2c-a3e5-fd6eda822f04
DOI
10.1101/2025.08.24.671996
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
AVDB: The Arab Variation and Disease Burden DatabaseDOI 10.1101/2025.08.24.671996
Pathogenic variation underlying rare diseases in an Arab Population: implications for screening programsSemantic proximity
Spectrum of Genetic Disorders and Gene Variants in the United Arab Emirates National Population: Insights from the CTGA DatabaseSemantic proximity
DALIA- a comprehensive resource of Disease Alleles in Arab population.Semantic proximity
Common disease-associated gene variants in a Saudi Arabian populationSemantic proximity
Burden of Mendelian disorders in a large Middle Eastern biobank.Semantic proximity
Arab genetic disease database (AGDDB): a population-specific clinical and mutation database.Semantic proximity
al mena: a comprehensive resource of human genetic variants integrating genomes and exomes from Arab, Middle Eastern and North African populations.Semantic proximity
Pharmacogenomic survey of Qatari populations using whole-genome and exome sequences.Semantic proximity
Assessment of coding region variants in Kuwaiti population: implications for medical genetics and population genomicsSemantic proximity
Recommendations for genetic variation data capture in developing countries to ensure a comprehensive worldwide data collection.Semantic proximity
CTGA: the database for genetic disorders in Arab populations.Semantic proximity
PanelAppRex aggregates disease gene panels and facilitates sophisticated searchSemantic proximity
Select a neighboring publication to make it the new centre.