Article
Recommendations for genetic variation data capture in developing countries to ensure a comprehensive worldwide data collection.
Human mutation - 1 Jan 2011
Patrinos George P, Al Aama Jumana, Al Aqeel Aida, Al-Mulla Fahd, Borg Joseph, Devereux Andrew, Felice Alex E, Macrae Finlay, Marafie Makia J, Petersen Michael B, Qi Ming, Ramesar Rajkumar S, Zlotogora Joel, Cotton Richard G H
Abstract excerpt
Developing countries have significantly contributed to the elucidation of the genetic basis of both common and rare disorders, providing an invaluable resource of cases due to large family sizes, consanguinity, and potential founder effects. Moreover, the recognized depth of genomic variation in indigenous African populations, reflecting the ancient origins of humanity on the African continent, and the effect of...
Topics
- Data Collection
- Developing Countries
- Genetic Variation
- Humans