Article

<i>De Novo</i> Peptide Sequencing Reveals a Vast Cyclopeptidome in Human Gut and Other Environments

2019-01-16

Abstract excerpt

<h4>ABSTRACT</h4> Cyclic and branch cyclic peptides (cyclopeptides) represent an important class of bioactive natural products that include many antibiotics and anti-tumor compounds. However, little is known about cyclopeptides in the human gut, despite the fact that humans are constantly exposed to them. To address this bottleneck, we developed the CycloNovo algorithm for de novo cyclopeptide sequencing that em...

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Literature Corpus work: f856efb2-18b5-5f11-93f5-ce4a4d8a1b93
DOI: 10.1101/521872

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