Article

Identifying High-Dimensional Genomic Factors Modulating Biological Networks Across Multi-Omics Data

2025-12-22

Abstract excerpt

Biological traits such as genes, metabolites, and microbial taxa interact within complex networks, yet how genomic factors shape these interactions remains poorly understood. Here, we introduce GFBioNet, a computationally efficient method for identifying factors that modulate direct associations between biological traits within network models. Our two-stage strategy first estimates a baseline network using Gaussia...

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Literature Corpus work: f84c659a-7550-570a-a91f-a7967ede8026
DOI: 10.64898/2025.12.18.695273

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