Article
A harmonized public resource of deeply sequenced diverse human genomes.
Genome research - 25 Jun 2024
Koenig Zan, Yohannes Mary T, Nkambule Lethukuthula L, Zhao Xuefang, Goodrich Julia K, Kim Heesu Ally, Wilson Michael W, Tiao Grace, Hao Stephanie P, Sahakian Nareh, Chao Katherine R, Walker Mark A, Lyu Yunfei, Rehm Heidi L, Neale Benjamin M, Talkowski Michael E, Daly Mark J, Brand Harrison, Karczewski Konrad J, Atkinson Elizabeth G, Martin Alicia R
Abstract excerpt
Underrepresented populations are often excluded from genomic studies owing in part to a lack of resources supporting their analyses. The 1000 Genomes Project (1kGP) and Human Genome Diversity Project (HGDP), which have recently been sequenced to high coverage, are valuable genomic resources because of the global diversity they capture and their open data sharing policies. Here, we harmonized a high-quality set of...
Topics
- Humans
- Genome, Human
- Databases, Genetic
- Human Genome Project
- High-Throughput Nucleotide Sequencing
- Genetic Variation
- Genomics