Article

The gut microbiome of infants with hypoplastic left heart syndrome is enriched in pathobionts and exhibits altered responses to nutritional intervention

2026-08-02

Abstract excerpt

<h4>ABSTRACT</h4> Congenital heart disease (CHD) can expose infants to chronic cyanosis, altered intestinal perfusion, and prolonged hospitalization. Altered gut microbiota has been linked to inflammation and gut barrier dysfunction in CHD cohorts, but few studies have examined whether cardiac severity and oxygenation shape microbial function, or whether this can be leveraged nutritionally, particularly for hypop...

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Literature Corpus work: f7e4b9db-cef1-56b3-934b-72dcc71c901d
DOI: 10.64898/2026.07.29.740758

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