Article

Characterization of clinical and genetic spectrum of Chinese patients with cystic fibrosis

2020-03-30

Abstract excerpt

<title>Abstract</title> <p>Background Cystic fibrosis (CF) is a rare autosomal recessive disorder caused by biallelic mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The clinical features and mutation spectrum of CF have been well characterized in Caucasians, while limited studies were conducted in Chinese patients. Subjects and methods A total of 20 individuals from 19 famili...

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Literature Corpus work: f7be90d9-9216-5a2c-b7e8-aaf75e8f444e
DOI: 10.21203/rs.2.20219/v2

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