Article

Attention-Enhanced U-Net Segmentation for Reliable Detection of Circulating Tumor-Associated Cells

2026-05-14

Abstract excerpt

<title>Abstract</title> <p>Background Circulating tumor-associated cells (CTACs) are rare among peripheral blood nucleated cells (PBNCs), posing a challenge to use them as Multi Cancer Early Detection (MCED) tool. We developed an attention-gated U-Net model for pixel-level CTAC discrimination that preserves key morphological and fluorescence details. Methods Model suitability was explored in asymptomatic indivi...

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Literature Corpus work: f7b3376c-208c-5b42-a328-85b20a280dee
DOI: 10.21203/rs.3.rs-9270114/v1

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