Article

Attention-Enhanced U-Net Segmentation for Reliable Detection of Circulating Tumor-Associated Cells

2026-03-09

Abstract excerpt

<h4>Background</h4> Circulating tumor associated cell (CTAC) detection-based multi-cancer early detection (MCED) strategies may be hindered by the rarity of CTACs among millions of peripheral blood nucleated cells (PBNCs). We developed an advanced U-Net-based encoder-decoder model for pixel-level CTAC discrimination that integrates attention-gated skip connections to preserve morphological and fluorescence detail...

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Literature Corpus work: 847b798c-d2df-5eea-9b77-0b0cb0033ff0
DOI: 10.64898/2026.03.07.26347846

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