Article

Reverse engineering of the pattern recognition receptor FLS2 reveals key design principles of broader recognition spectra against evading flg22 epitopes

2024-10-13

Abstract excerpt

In the ongoing plant-pathogen arms race, plants employ pattern recognition receptors (PRRs) to recognize pathogen-associated molecular patterns (PAMPs), while in successful pathogens, PAMPs can evolve to evade detection. Engineering PRRs to recognize evading PAMPs could potentially generate broad-spectrum and durable disease resistance. In this study, we reverse-engineered two natural FLAGELLIN SENSING 2 (FLS2) va...

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Literature Corpus work: f7725bcf-8002-57f4-ac4b-243a82c417e9
DOI: 10.1101/2024.10.10.617594

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