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Article

Ligand-induced endocytosis of the pattern recognition receptor FLS2 in Arabidopsis.

Genes & development - 1 Mar 2006

Robatzek Silke, Chinchilla Delphine, Boller Thomas

Abstract excerpt

Pattern-recognition receptors (PRRs) trigger innate immune responses in animals and plants. One such PRR is the flagellin receptor FLS2 in Arabidopsis. Here, we demonstrate that a functional fusion of FLS2 to the green fluorescent protein (GFP) resides in cell membranes of most tissues. Stimulation with the flagellin epitope flg22 induces its transfer into intracellular mobile vesicles, followed by degradation....

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Identifiers

PMID: 16510871
DOI: 10.1101/gad.366506
PMCID: PMC1410809

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Ligand-induced endocytosis of the pattern recognition receptor FLS2 in Arabidopsis.PMID 16510871Read ↗

Sensitivity to Flg22 is modulated by ligand-induced degradation and de novo synthesis of the endogenous flagellin-receptor FLAGELLIN-SENSING2.Semantic proximity Read ↗

The Arabidopsis receptor kinase FLS2 binds flg22 and determines the specificity of flagellin perception.Semantic proximity Read ↗

Variable Effects of C-Terminal Fusions on FLS2 Function: Not All Epitope Tags Are Created Equal.Semantic proximity Read ↗

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Tissue-specific FLAGELLIN-SENSING 2 (FLS2) expression in roots restores immune responses in Arabidopsis fls2 mutants.Semantic proximity Read ↗

Loss of Arabidopsis thaliana Dynamin-Related Protein 2B reveals separation of innate immune signaling pathways.Semantic proximity Read ↗

Reverse engineering of the pattern recognition receptor FLS2 reveals key design principles of broader recognition spectra against evading flg22 epitopesSemantic proximity Read ↗

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Pattern recognition receptors require N-glycosylation to mediate plant immunity.Semantic proximity Read ↗

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FLS2: an LRR receptor-like kinase involved in the perception of the bacterial elicitor flagellin in Arabidopsis.Semantic proximity Read ↗

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