Back to search

Article

TripletGO: Integrating Transcript Expression Profiles with Protein Homology Inferences for High-Accuracy Gene Function Annotations

2021-11-27

Abstract excerpt

Gene Ontology (GO) has been widely used to annotate functions of genes and gene products. We proposed a new method (TripletGO) to deduce GO terms of protein-coding and non-coding genes, through the integration of four complementary pipelines built on transcript expression profiling, genetic sequence alignment, protein sequence alignment and naive probability, respectively. TripletGO was tested on a large set of 5,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
f74c3fa6-9343-53fa-aa64-6ddf32253bf7
DOI
10.1101/2021.11.25.470058
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
TripletGO: Integrating Transcript Expression Profiles with Protein Homology Inferences for High-Accuracy Gene Function AnnotationsDOI 10.1101/2021.11.25.470058
Select a neighboring publication to make it the new centre.