Article

A novel <i>hemA</i> mutation is responsible for small colony variant phenotype in <i>Escherichia coli</i>

2020-05-02

Abstract excerpt

We identified a small colony variant (SCV) of a clinical isolate of Escherichia coli from Malawi following sequential in vitro selection in sub-inhibitory concentrations of amoxicillin-clavulanic acid and gentamicin. The SCV was auxotrophic for hemin and had impaired biofilm formation compared to the ancestral isolates. A single novel nucleotide polymorphism (SNP) in hemA , which encodes a glutamyl-tRNA reducta...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f72e001d-70c0-5ff7-acd7-afbec4c8f38b
DOI: 10.1101/2020.05.01.073478

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A novel <i>hemA</i> mutation is responsible for small colony variant phenotype in <i>Escherichia coli</i>DOI 10.1101/2020.05.01.073478Read

A novel hemA mutation is responsible for a small-colony-variant phenotype in Escherichia coli.Semantic proximity Read

Staphylococcus aureus small colony variants: a challenge to microbiologists and clinicians.Semantic proximity Read

Evolution towards small colony variants of pandemic multidrug resistant ST131 <i>Escherichia coli</i> isolates from a 10-year wound infectionSemantic proximity Read

Spontaneous genomic variation as a survival strategy of nosocomial <i>S. haemolyticus</i>Semantic proximity Read

Analysis of <i>in-patient</i> evolution of <i>Escherichia coli</i> reveals potential links to relapse of bone and joint infectionsSemantic proximity Read

Biochemical traits that <i>Escherichia coli</i> evolved during its adaption to the gastrointestinal tract of humansSemantic proximity Read

A yigP mutant strain is a small colony variant of E. coli and shows pleiotropic antibiotic resistance.Semantic proximity Read

The Physiological and Molecular Characterization of a Small Colony Variant of Escherichia coli and Its Phenotypic Rescue.Semantic proximity Read

Genomic and Transcriptomic Profiling of Phoenix ColoniesSemantic proximity Read

Differential Gene Expression Analysis of a Small Colony Variant of <i>Escherichia coli</i> K-12Semantic proximity Read

Insights into the molecular basis of L-form formation and survival in Escherichia coli.Semantic proximity Read

Inactivation of genes in oxidative respiration and iron acquisition pathways in pediatric clinical isolates of small-colony variant <i>Enterobactericeae</i>Semantic proximity Read