Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel hemA mutation is responsible for a small-colony-variant phenotype in Escherichia coli.

Microbiology (Reading, England) - 1 Mar 2021

Hubbard Alasdair T M, Bulgasim Issra, Roberts Adam P

Abstract excerpt

We identified a small colony variant (SCV) of an amoxicillin/clavulanic acid-resistant derivative of a clinical isolate of Escherichia coli from Malawi, which was selected for in vitro in a subinhibitory concentration of gentamicin. The SCV was auxotrophic for hemin and had impaired biofilm formation compared to the ancestral isolates. A single novel nucleotide polymorphism (SNP) in hemA, which encodes a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aldehyde Oxidoreductases
Share to Anti-Bacterial Agents
Share to Drug Resistance, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Escherichia coli

Share to Escherichia coli Infections

Share to Gentamicins

Share to Microbial Sensitivity Tests

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 32762803
DOI: 10.1099/mic.0.000962

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel hemA mutation is responsible for a small-colony-variant phenotype in Escherichia coli.PMID 32762803Read ↗

A novel <i>hemA</i> mutation is responsible for small colony variant phenotype in <i>Escherichia coli</i>Semantic proximity Read ↗

Staphylococcus aureus small colony variants: a challenge to microbiologists and clinicians.Semantic proximity Read ↗

Genomic and Transcriptomic Profiling of Phoenix ColoniesSemantic proximity Read ↗

The Physiological and Molecular Characterization of a Small Colony Variant of Escherichia coli and Its Phenotypic Rescue.Semantic proximity Read ↗

The Clinical Significance of Staphylococcus aureus Small Colony VariantsSemantic proximity Read ↗

A yigP mutant strain is a small colony variant of E. coli and shows pleiotropic antibiotic resistance.Semantic proximity Read ↗

Insights into the molecular basis of L-form formation and survival in Escherichia coli.Semantic proximity Read ↗

The transmutation of Escherichia coli ATCC 25922 to small colony variants (SCVs) E. coli strain as a result of exposure to gentamicin.Semantic proximity Read ↗

Growth control of small-colony variants by genetic regulation of the hemin uptake system.Semantic proximity Read ↗

The small colony variant (SCV) concept -- the role of staphylococcal SCVs in persistent infections.Semantic proximity Read ↗

Molecular characterization of a carbon dioxide-dependent Escherichia coli small-colony variant isolated from blood cultures.Semantic proximity Read ↗

Haem toxicity provides a competitive advantage to the clinically relevant Staphylococcus aureus small colony variant phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.