Article

A delayed ovulation of Progestin-Primed Ovarian Stimulation (PPOS) by down-regulating the LHCGR/PGR pathway

2022-12-22

Abstract excerpt

PPOS as a new clinic ovulation stimulation protocol, its role in ovulation and regulatory mechanism is not clear. The clinical PPOS protocol was simulated in mice, and it had a delayed ovulation than the control group at 12.5 hours after hCG trigger. The suppressed LH level of PPOS group led to the reduced expression of LHCGR on the preovulatory follicles before trigger, and significantly decreased the following p...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f706369f-d8ad-5df3-8326-b8b75a01cdb5
DOI: 10.21203/rs.3.rs-2327379/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A delayed ovulation of Progestin-Primed Ovarian Stimulation (PPOS) by down-regulating the LHCGR/PGR pathwayDOI 10.21203/rs.3.rs-2327379/v1Read

Identification of new ovulation-related genes in humans by comparing the transcriptome of granulosa cells before and after ovulation triggering in the same controlled ovarian stimulation cycleSemantic proximity Read

Prostaglandin E2 involvement in mammalian female fertility: ovulation, fertilization, embryo development and early implantationSemantic proximity Read

Ovarian Steroids: The Good, the Bad, and the Signals that Raise ThemSemantic proximity Read

Current mechanisms of primordial follicle activation and new strategies for fertility preservationSemantic proximity Read

Comparison of the different animal modeling and therapy methods of premature ovarian failure in animal modelSemantic proximity Read

Inducers and Inhibitors of Pyroptotic Death of Granulosa Cells in Models of Premature Ovarian Insufficiency and Polycystic Ovary SyndromeSemantic proximity Read

Expression of Tissue Factor and Tissue Factor Pathway Inhibitors during Ovulation in Rats: A Potential Biomarker for Ovarian Hyperstimulation SyndromeSemantic proximity Read

Ovulation, A Sign of HealthSemantic proximity Read

The high concentration of progesterone is harmful for endometrial receptivity and decidualizationSemantic proximity Read

Follicular development and endometrial receptivity of different androgen phenotypes in polycystic ovary syndromeSemantic proximity Read

Ovulation Induction in Polycystic Ovarian Syndrome: A Review to Contemporary approachesSemantic proximity Read

In Vitro Activation Early Follicles: From the Basic Science to the Clinical PerspectivesSemantic proximity Read