Article

Tetrandrine-Driven Autophagy Suppresses SARS-CoV-2 Replication by Modulating Cholesterol and IGF Signaling Pathways

2025-07-03

Abstract excerpt

<title>Abstract</title> <p> SARS-CoV-2 exploits multiple host cellular processes, including autophagy—a critical intracellular degradation pathway—to facilitate viral replication and evade immune detection. Tetrandrine, a natural bis-benzylisoquinoline alkaloid derived from <italic>Stephania tetrandra</italic> , has been reported to modulate autophagy and exhibits potential antiviral properties. In this study,...

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Literature Corpus work: f6e3c0eb-ce9b-579a-8a75-02fca74d1970
DOI: 10.21203/rs.3.rs-6958516/v1

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