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Applications of the Novel Quantitative Pharmacophore Activity Relationship Method QPhAR in Virtual Screening and Lead-optimization

2022-07-29

Abstract excerpt

Pharmacophores are an established concept for the modelling of ligand-receptor interactions based on the abstract representations of stereoelectronic molecular features. They became widely popular as filters for the fast virtual screening of large compound libraries. Until today a lot of effort has been put into the development of sophisticated algorithms and strategies to increase the computational efficiency of...

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Literature Corpus work
f6bd0532-b507-501a-b2d3-7d4a6e54b9a9
DOI
10.20944/preprints202207.0453.v1
Open publication

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Applications of the Novel Quantitative Pharmacophore Activity Relationship Method QPhAR in Virtual Screening and Lead-optimizationDOI 10.20944/preprints202207.0453.v1
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