Article
Adhesion-Peptide Conjugates of Thermo-Responsive Polymers Co-Electrospun into Fibrous Scaffolds Enable Growth and Enzyme-Free Recovery of Quiescent Human Corneal Stromal Cells (hCSCs)
2019-08-08
Abstract excerpt
Here we report the development of a PLA/thermo-responsive (PDEGMA) blend 3D electrospun fibre-based scaffold to create an enzymatic-free 3D cell culture platform for the expansion of mammalian cells with the desired phenotype for clinical use. Human corneal stromal cells (hCSCs) were used as an exemplar as they have been observed to de-differentiate to an undesirable myo-fibroblastic phenotype when cultured by con...
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Identifiers and source
- Literature Corpus work
- f6a575b9-32dc-54a7-b6e0-752799dd383b
- DOI
- 10.26434/chemrxiv.9307844.v2
