P-hacking in clinical trials and how incentives shape the distribution of results across phases^*

Abstract excerpt

Clinical research should conform to high standards of ethical and scientific integrity, given that human lives are at stake. However, economic incentives can generate conflicts of interest for investigators, who may be inclined to withhold unfavorable results or even tamper with data in order to achieve desired outcomes. To shed light on the integrity of clinical trial results, this paper systematically analyzes t...

Topics

Open a Topic to create a Post that cites this publication.

• Antiporters
• Bayes Theorem
• Cystic Fibrosis
• Likelihood Functions
• Models, Statistical
• Probability
• Sample Size
• Sulfate Transporters

Identifiers and source

Literature Corpus work

f65d3b42-a4db-586b-90d2-a73c1b368782

DOI

10.1101/19001495