Article

PIK3CA Mutation Correlates With mTOR Pathway Expression But Not Clinical and Pathological Features in Fibro-Adipose Vascular Anomaly (FAVA)

2021-10-18

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>Fibro-adipose vascular anomaly (FAVA) is a rare and new entity of vascular anomaly. Activating mutations in the <italic>phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha</italic> (<italic>PIK3CA</italic>) gene were identified at a frequency of 62.5% in FAVA cases. The <italic>PIK3CA </italic>mutations excessively activate mammalian target of r...

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Literature Corpus work: f6456f4b-6464-5d21-a339-3f359ede8902
DOI: 10.21203/rs.3.rs-966735/v1

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