Article

Galectin approach to lower covid transmission - Drug Development for clinical use

2022-11-10

Abstract excerpt

<h4>Background</h4> SARS-CoV-2 vaccines play an important role in reducing disease severity, hospitalization, and death, although they failed to prevent the transmission of SARS-CoV-2 variants. Therefore, an effective inhibitor of galectin-3 (Gal-3) could be used to treat and prevent transmission of COVID-19. ProLectin-M (PL-M), a Gal-3 antagonist, has been shown to interact with Gal-3 and thus prevent cellular en...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f60eba18-cb4f-5aa9-9a1f-28f4bb79471c
DOI: 10.1101/2022.11.09.22282151

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Galectin approach to lower covid transmission - Drug Development for clinical useDOI 10.1101/2022.11.09.22282151Read

Galectin antagonist use in mild cases of SARS-CoV-2; pilot feasibility randomised, open label, controlled trialSemantic proximity Read

THE THERAPEUTIC POTENTIAL OF IVERMECTIN FOR COVID-19: A SYSTEMATIC REVIEW OF MECHANISMS AND EVIDENCESemantic proximity Read

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studiesSemantic proximity Read

Repositioning Ivermectin for Covid-19 treatment: Molecular mechanisms of action against SARS-CoV-2 replicationSemantic proximity Read

THE THERAPEUTIC POTENTIAL OF IVERMECTIN FOR COVID-19: A SYSTEMATIC REVIEW OF MECHANISMS AND EVIDENCESemantic proximity Read

Pharmacometric assessment of the <i>in vivo</i> antiviral activity of ivermectin in early symptomatic COVID-19Semantic proximity Read

The effect of early treatment with ivermectin on viral load, symptoms and humoral response in patients with mild COVID-19: a pilot, double-blind, placebo-controlled, randomized clinical trialSemantic proximity Read

Minimal impact of ivermectin on immune response and transcriptional profiles in naïve adults with mild COVID-19Semantic proximity Read

Research Into Potential Therapies Against COVID-19, With Focus On IvermectinSemantic proximity Read

Evolution of COVID-19 patients treated with ImmunoFormulation, a combination of nutraceuticals to reduce symptomatology and improve prognosis: a multi-centred, retrospective cohort studySemantic proximity Read

Research Into Potential Therapies Against COVID-19, With Focus On IvermectinSemantic proximity Read

Annual SZ® A Novel Formulation For COVID-19 Therapy Clinical Trial StudiesSemantic proximity Read