Article

Minimal impact of ivermectin on immune response and transcriptional profiles in naïve adults with mild COVID-19

2025-04-03

Abstract excerpt

Ivermectin (IVM), an antiparasitic drug, was repurposed to treat COVID-19 based on its in vitro antiviral effects. However, it was abandoned after multiple clinical trials reported a lack of efficacy. Immunomodulatory effects have been proposed but remain unclear, yet they may be relevant given IVM use for other infections. We assessed the IVM immunomodulatory effect in 24 participants from a clinical trial evalua...

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Literature Corpus work: 94715eab-66c6-5045-a707-5e9dc9e6bcf2
DOI: 10.1101/2025.03.31.646276

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