Article

Main checkpoints of the JNK-MAPK pathway using the Boolean network simulation following HTLV-1-associated leukemia

2024-07-16

Abstract excerpt

The c-Jun N-terminal kinase (JNK) pathway is a signal transduction pathway that plays a critical role in cell growth and survival. Its dysregulation is related to various cancers, including Adult T-cell Leukemia/Lymphoma (ATLL), an aggressive peripheral T-cell malignancy due to infection with the Human T-cell lymphotropic virus type 1 (HTLV-1). ATLL currently has no vaccine or definitive treatment. This research a...

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Literature Corpus work: f45d4dee-e143-5043-926e-95a01eee464f
DOI: 10.22541/au.172114306.62981294/v1

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