Article

Therapeutic ultrasound enables rapid and robust activation of ROS-responsive prodrugs in vivo

2026-06-22

Abstract excerpt

<title>Abstract</title> <p>Reactive oxygen species (ROS)-responsive prodrugs offer a route to disease-selective drug activation, but their in vivo performance is often constrained by heterogeneous ROS production, short ROS lifetimes and reductive quenching. Therapeutic ultrasound can generate reactive species locally and on demand in deep tissues, yet whether conventional ROS-responsive masking groups respond pro...

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Literature Corpus work: f44f9f66-08b0-57fc-9614-6a03a39d5f30
DOI: 10.21203/rs.3.rs-9984684/v1

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