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Article

Biodegradable Nanosonosensitizers with the Multiple Modulation of Tumor Microenvironment for Enhanced Sonodynamic Therapy.

International journal of nanomedicine - 1 Jan 2021

Zhou Hang, Sun Jiawei, Wu Jiaqi, Wei Hong, Zhou Xianli

Abstract excerpt

BACKGROUND: The specific microenvironment of solid tumors, which is characterized by hypoxia, overexpression of glutathione (GSH), and high accumulation of anti-inflammatory tumor-associated macrophages (TAMs), limits the efficiency of sonodynamic therapy (SDT). METHOD AND RESULTS: Herein, a multifunctional nanoplatform was engineered to modulate the tumor microenvironment for highly efficient SDT. In this...

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Identifiers

PMID: 33854312
DOI: 10.2147/IJN.S297571
PMCID: PMC8040090

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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