Article

Chemo-sEVs release in cisplatin-resistance ovarian cancer cells are regulated by the lysosomal function

2023-02-04

Abstract excerpt

<h4>ABSTRACT</h4> Ovarian cancer (OvCa) is an aggressive disease usually treated with cisplatin (CDDP)-based therapy. However, among the different types of cancers treated with CDDP, OvCa commonly develops chemoresistance to this treatment. The small extracellular vesicles (sEVs) play a central role in chemoresistance. In response to chemotherapy, resistant cells secrete sEVs named chemo-sEVs characterized by spe...

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Literature Corpus work: f44d8412-0bfe-51b9-929f-da3a5715657b
DOI: 10.1101/2023.02.03.526974

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