Article

The Curcumin Analog (PAC) Has Anti-Oral Cancer Properties Through Impairing Pro-Survival Signaling Pathways and Activating the Cell Death Processes Apoptosis and Autophagy

2020-12-21

Abstract excerpt

PAC (3,5- Bis (4-hydroxy-3-methoxybenzylidene)-N-methyl-4-piperidone), a novel bioactive curcumin analog, has been reported to have anticancer properties against various tumors. However, the anti-cancer effects of PAC on oral cavity squamous cell carcinoma (OC-SCC) were not studied yet. Our aim is to investigate the anti-oral cancer properties of PAC in vitro, and determine the molecular mechanisms underlying thes...

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Literature Corpus work: f344b938-52cc-55bf-9d7a-49a4f50c0f7b
DOI: 10.21203/rs.3.rs-128652/v1

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