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Curcumin as an Alternative Epigenetic Modulator: Mechanism of Action and Potential Effects

4 Jun 2019

Abstract excerpt

Curcumin (a polyphenolic compound in turmeric) is famous for its potent anti-inflammatory, anti-oxidant, and anti-cancer properties, and has a great potential to act as an epigenetic modulator. The epigenetic regulatory roles of curcumin include the inhibition of DNA methyltransferases (DNMTs), regulation of histone modifications via the regulation of histone acetyltransferases (HATs) and histone deacetylases...

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PMID: 31214247
DOI: 10.3389/fgene.2019.00514

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